Fluid-Based Protein Biomarkers in Traumatic Brain Injury: The View from the BedsideFluid-Based Protein Biomarkers in Traumatic Brain Injury: The View from the Bedside International Journal of Molecular ScienceInternational Journal of Molecular Science We review the current status of biomarker research and discuss how we can integrate existing markers into current clinical practice and what additional biomarkers do we need to improve diagnoses and to guide therapy and to assess treatment efficacy. Furthermore, we argue for employing machine learning (ML) capabilities to integrate the protein biomarker data with other established, routinely used clinical diagnostic tools, to provide the clinician with actionable information to guide medical intervention.